It was a perfect opener at Frigid Fenway, as the Sox, apparently aided by Bill Belichick's Florida presence, put two TDs on the board to paste the Mariners 14-3.
Josh Beckett (2-0) delivered seven quality innings of two-hit ball, allowing no walks and eight strikeouts. Beckett fanned Ichiro three times on fastballs away.
Jason Varitek added three hits to break out of his early season doldrums, Kevin Youkilis added three hits, and J.D. Drew hit his first Boston homerun into the centerfield bleachers.
Terry Francona rested his regulars starting in the fifth inning.
Brendan Donnelly was ejected in the eighth for hitting nemesis Jose Guillen.
Mike Timlin pitched the ninth after having been recalled from a rehab assignment. Javy Lopez was optioned to Pawtucket to make room for Timlin.
Tomorrow night features the Sox-Mariners on National TV (ESPN2) with Daisuke Matsuzaka making his Fenway debut.